mouse MFGE8 shRNA silencing Adenovirus

Product Info

Knockdown

>50% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Mfge8

Gene Name

milk fat globule-EGF factor 8 protein

Gene ID

17304

Gene Synonyms

AA408458; AI325141; lactadherin; MFG-E8; Mfgm; MP47; P47; SED1

ORF Size

1281 bp

RefSeq#

NM_008594

Gene Description

Plays an important role in the maintenance of intestinal epithelial homeostasis and the promotion of mucosal healing. Promotes VEGF-dependent neovascularization (By similarity). Contributes to phagocytic removal of apoptotic cells in many tissues. Specific ligand for the alpha-v/beta-3 and alpha-v/beta-5 receptors. Also binds to phosphatidylserine-enriched cell surfaces in a receptor-independent manner. Zona pellucida-binding protein which may play a role in gamete interaction. Binds specifically to rotavirus and inhibits its replication|Function: Medin is the main constituent of aortic medial amyloid.

UniGene ID

Mm.1451