mouse MCM4 shRNA silencing Adenovirus

Name 
Ad-m-MCM4-shRNA
Cat No 
shADV-264375
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Mcm4.

shADV-264375
Ad-m-MCM4-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Mcm4 (minichromosome maintenance complex component 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
19G; AI325074; AU045576; Cdc21; mcdc21; Mcmd4; mKIAA4003
Description (Vector)
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity.
Gene ID
17217
Gene Name (Vector)
minichromosome maintenance complex component 4
Gene Symbol
Mcm4
ORF Size (aa)
2589
ORF Size (bp)
2589 bp
RefSeq ID
NM_008565
RefSeq Synonyms
NM_008565, BC013094,
Species
mouse
UniGene ID
Mm.472867

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.