mouse MAS1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Mas1.
shADV-264280
Ad-m-MAS1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Mas1 (MAS1 oncogene). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
Mas-1; Mgra
Description (Vector)
Receptor for angiotensin 1-7 (By similarity). Acts specifically as a functional antagonist of AGTR1 (angiotensin-2 type 1 receptor), although it up-regulates AGTR1 receptor levels. Positive regulation of AGTR1 levels occurs through activation of the G-proteins GNA11 and GNAQ, and stimulation of the protein kinase C signaling cascade. The antagonist effect on AGTR1 function is probably due to AGTR1 being physically altered by MAS1.
Gene ID
17171
Gene Name (Vector)
MAS1 oncogene
Gene Symbol
Mas1
ORF Size (aa)
975
RefSeq ID
NM_008552
RefSeq Synonyms
NM_008552, BC144900, BC125537, BC120790,
Species
mouse
UniGene ID
Mm.425994
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.