mouse MARK3 shRNA silencing Adenovirus

Name 
Ad-m-MARK3-shRNA
Cat No 
shADV-264272
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Mark3.

shADV-264272
Ad-m-MARK3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Mark3 (MAP/microtubule affinity regulating kinase 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
60
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
1600015G02Rik; A430080F22Rik; C-TAK1; Emk2; ETK-1; ETK1; MPK10
Description (Vector)
Involved in the specific phosphorylation of microtubule-associated proteins for tau, MAP2 and MAP4. Phosphorylates CDC25C on 'Ser-216'. Regulates localization and activity of some histone deacetylases by mediating phosphorylation of HDAC7, promoting subsequent interaction between HDAC7 and 14-3-3 and export from the nucleus.
Gene ID
17169
Gene Name (Vector)
MAP/microtubule affinity regulating kinase 3
Gene Symbol
Mark3
ORF Size (aa)
1287
ORF Size (bp)
1287 bp
RefSeq ID
NM_022801
RefSeq Synonyms
NM_022801, NM_021516, BC026445,
Species
mouse
UniGene ID
Mm.425769

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.