mouse LPIN1 shRNA silencing Adenovirus

Name 
Ad-m-LPIN1-shRNA
Cat No 
shADV-263781
Availability
Immediate

This is an Adenovirus expressing shRNA for silencing of Mouse Lpin1.

shADV-263781
Ad-m-LPIN1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Lpin1 (lipin 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
4631420P06; fld; Kiaa0188; Lipin1; mKIAA0188
Description (Vector)
Plays important roles in controlling the metabolism of fatty acids at differents levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis in the reticulum endoplasmic membrane. Acts also as a nuclear transcriptional coactivator for PPARGC1A/PPARA to modulate lipid metabolism gene expression (By similarity). Is involved in adipocyte differentiation. May also be involved in mitochondrial fission by converting phosphatidic acid to diacylglycerol (By similarity).
Gene ID
14245
Gene Name (Vector)
lipin 1
Gene Symbol
Lpin1
ORF Size (aa)
2775
ORF Size (bp)
2775 bp
RefSeq ID
NM_172950
RefSeq Synonyms
NM_172950, NM_015763, NM_001130412, BC042462,
Species
mouse
UniGene ID
Mm.153625

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.