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mouse LMCD1 shRNA silencing Adenovirus

Name 
Ad-m-LMCD1-shRNA
Cat No 
shADV-263515
Availability
Immediate

This is an Adenovirus expressing shRNA for silencing of Mouse Lmcd1.

shADV-263515
Ad-m-LMCD1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Lmcd1 (LIM and cysteine-rich domains 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AW455500; AW553074; dyxin
Description (Vector)
Transcriptional cofactor that restricts GATA6 function by inhibiting DNA-binding, resulting in repression of GATA6 transcriptional activation of downstream target genes. Represses GATA6-mediated trans activation of lung- and cardiac tissue-specific promoters. Inhibits DNA-binding by GATA4 and GATA1 to the cTNC promoter (By similarity). Plays a critical role in the development of cardiac hypertrophy via activation of calcineurin/nuclear factor of activated T-cells signaling pathway.
Gene ID
30937
Gene Name (Vector)
LIM and cysteine-rich domains 1
Gene Symbol
Lmcd1
ORF Size (aa)
1098
RefSeq ID
NM_144799
RefSeq Synonyms
NM_144799, BC019124,
Species
mouse
UniGene ID
Mm.234441

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.