mouse KDM2A shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Kdm2a.
shADV-262758
Ad-m-KDM2A-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Kdm2a (lysine (K)-specific demethylase 2A). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
100043628; 5530401A10Rik; AA589516; AW536790; Cxxc8; Fbl11; Fbl7; Fbxl11; Gm4560; Jhdm1; Jhdm1a; lalina
Description (Vector)
Histone demethylase that specifically demethylates 'Lys-36' of histone H3, thereby playing a central role in histone code. Preferentially demethylates dimethylated H3 'Lys-36' residue while it has weak or no activity for mono- and tri-methylated H3 'Lys-36'. May also recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation. Required to maintain the heterochromatic state. Associates with centromeres and represses transcription of small non-coding RNAs that are encoded by the clusters of satellite repeats at the centromere. Required to sustain centromeric integrity and genomic stability, particularly during mitosis.
Gene ID
225876
Gene Name (Vector)
lysine (K)-specific demethylase 2A
Gene Symbol
Kdm2a
ORF Size (aa)
2508
ORF Size (bp)
2508 bp
RefSeq ID
NM_001001984
RefSeq Synonyms
NM_001001984, BC076576,
Species
mouse
UniGene ID
Mm.31941
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.