mouse ILKAP shRNA silencing Adenovirus

Name 
Ad-m-ILKAP-shRNA
Cat No 
shADV-262207
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Ilkap.

shADV-262207
Ad-m-ILKAP-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Ilkap (integrin-linked kinase-associated serine/threonine phosphatase 2C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
0710007A14Rik; 1600009O09Rik; PP2C-DELTA
Description (Vector)
Protein phosphatase that may play a role in regulation of cell cycle progression via dephosphorylation of its substrates whose appropriate phosphorylation states might be crucial for cell proliferation. Selectively associates with integrin linked kinase (ILK), to modulate cell adhesion and growth factor signaling. Inhibits the ILK-GSK3B signaling axis and may play an important role in inhibiting oncogenic transformation.
Gene ID
67444
Gene Name (Vector)
integrin-linked kinase-associated serine/threonine phosphatase 2C
Gene Symbol
Ilkap
ORF Size (aa)
810
RefSeq ID
NM_023343
RefSeq Synonyms
NM_023343, BC027439, BC026953,
Species
mouse
UniGene ID
Mm.337240

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.