mouse IKZF1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Ikzf1.
shADV-262075
Ad-m-IKZF1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Ikzf1 (IKAROS family zinc finger 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
5832432G11Rik; hlk-1; Ikaros; LyF-1; mKIAA4227; Zfpn1a1; Znfn1a1
Description (Vector)
Transcription regulator of hematopoietic cell differentiation. Binds gamma-satellite DNA. Binds with higher affinity to gamma satellite A. Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delta gene. Repressor of the TDT (terminal deoxynucleotidyltransferase) gene during thymocyte differentiation. Regulates transcription through association with both HDAC-dependent and HDAC-independent complexes. Targets the 2 chromatin-remodeling complexes, NuRD and BAF (SWI/SNF), in a single complex (PYR complex), to the beta-globin locus in adult erythrocytes. Increases normal apoptosis in adult erythroid cells. Confers early temporal competence to retinal progenitor cells (RPCs) (By similarity).
Gene ID
22778
Gene Name (Vector)
IKAROS family zinc finger 1
Gene Symbol
Ikzf1
ORF Size (aa)
1287
ORF Size (bp)
1287 bp
RefSeq ID
NM_009578
RefSeq Synonyms
NM_009578, NM_001301868, NM_001301866, NM_001301865, NM_001301863, NM_001025597, BC138789,
Species
mouse
UniGene ID
Mm.103545
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.