mouse HOPX shRNA silencing Adenovirus

Name
Ad-m-HOPX-shRNA

Cat No
shADV-261556

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Hopx.

shADV-261556

Ad-m-HOPX-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Hopx (HOP homeobox). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

1110018K11Rik; 1200015P04Rik; 2300002F06Rik; AI848177; AW490897; Cameo; Hdop; Hod; Hop; Ob1; Obl; Toto

Description (Vector)

Atypical homeodomain protein which does not bind DNA and is required to modulate cardiac growth and development. Acts via its interaction with SRF, thereby modulating the expression of SRF-dependent cardiac-specific genes and cardiac development. Prevents SRF-dependent transcription either by inhibiting SRF binding to DNA or by recruiting histone deacetylase (HDAC) proteins that prevent transcription by SRF. Overexpression causes cardiac hypertrophy (By similarity). May act as a tumor suppressor.

Gene ID

74318

Gene Name (Vector)

HOP homeobox

Gene Symbol

Hopx

ORF Size (aa)

222

ORF Size (bp)

222 bp

RefSeq ID

NM_175606

RefSeq Synonyms

NM_175606, NM_001159901, NM_001159900, BC024546,

Species

mouse

UniGene ID

Mm.181852

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.