mouse HMGB1 shRNA silencing Adenovirus

Name 
Ad-m-HMGB1-shRNA
Cat No 
shADV-261448
Availability
Immediate

This is an Adenovirus expressing shRNA for silencing of Mouse Hmgb1.

shADV-261448
Ad-m-HMGB1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Hmgb1 (high mobility group box 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
HMG-1; Hmg1; p30; SBP-1
Description (Vector)
DNA binding proteins that associates with chromatin and has the ability to bend DNA. Binds preferentially single-stranded DNA. Involved in V(D)J recombination by acting as a cofactor of the RAG complex. Acts by stimulating cleavage and RAG protein binding at the 23 bp spacer of conserved recombination signal sequences (RSS). Heparin-binding protein that has a role in the extension of neurite-type cytoplasmic processes in developing cells (By similarity).
Gene ID
15289
Gene Name (Vector)
high mobility group box 1
Gene Symbol
Hmgb1
ORF Size (aa)
648
ORF Size (bp)
648 bp
RefSeq ID
NM_010439
RefSeq Synonyms
NM_010439, NM_001313894, BC111468, BC110667, BC100312, BC094030, BC091741, BC085090, BC083067, BC064790, BC008565, BC006586,
Species
mouse
UniGene ID
Mm.313345

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.