mouse HIST1H2BC shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Hist1h2bc.
shADV-261349
Ad-m-HIST1H2BC-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Hist1h2bc (histone cluster 1, H2bc). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2610022J01Rik; H2bfs; R74621
Description (Vector)
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling|Function: Has broad antibacterial activity. May contribute to the formation of the functional antimicrobial barrier of the colonic epithelium, and to the bactericidal activity of amniotic fluid.
Gene ID
68024
Gene Name (Vector)
histone cluster 1, H2bc
Gene Symbol
Hist1h2bc
ORF Size (aa)
381
RefSeq ID
NM_023422
RefSeq Synonyms
NM_023422, NM_001290380, BC019673,
Species
mouse
UniGene ID
Mm.261676
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.