mouse HIP1 shRNA silencing Adenovirus

Name 
Ad-m-HIP1-shRNA
Cat No 
shADV-261304
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Hip1.

shADV-261304
Ad-m-HIP1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Hip1 (huntingtin interacting protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
2610109B09Rik; A930014B11Rik; E130315I21Rik; mKIAA4113
Description (Vector)
Plays a role in clathrin-mediated endocytosis and trafficking. Involved in regulating AMPA receptor trafficking in the central nervous system in an NMDA-dependent manner. Enhances androgen receptor (AR)-mediated transcription. May act as a proapoptotic protein that induces cell death by acting through the intrinsic apoptosis pathway. Binds 3-phosphoinositides (via ENTH domain). May act through the ENTH domain to promote cell survival by stabilizing receptor tyrosine kinases following ligand-induced endocytosis. May play a functional role in the cell filament networks. May be required for differentiation, proliferation, and/or survival of somatic and germline progenitors.
Gene ID
215114
Gene Name (Vector)
huntingtin interacting protein 1
Gene Symbol
Hip1
ORF Size (aa)
2721
ORF Size (bp)
2721 bp
RefSeq ID
NM_146001
RefSeq Synonyms
NM_146001, BC017516,
Species
mouse
UniGene ID
Mm.280805

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.