mouse HDAC7 shRNA silencing Adenovirus

Name 
Ad-m-HDAC7-shRNA
Cat No 
shADV-261180
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Hdac7.

shADV-261180
Ad-m-HDAC7-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Hdac7 (histone deacetylase 7). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
50
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
5830434K02Rik; HD7; HD7a; Hdac7a; mFLJ00062
Description (Vector)
Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. Involved in muscle maturation by repressing transcription of myocyte enhancer factors such as MEF2A, MEF2B and MEF2C. During muscle differentiation, it shuttles into the cytoplasm, allowing the expression of myocyte enhancer factors (By similarity). May be involved in Epstein-Barr virus (EBV) latency, possibly by repressing the viral BZLF1 gene.
Gene ID
56233
Gene Name (Vector)
histone deacetylase 7
Gene Symbol
Hdac7
ORF Size (aa)
2817
ORF Size (bp)
2817 bp
RefSeq ID
NM_019572
RefSeq Synonyms
NM_019572, NM_001204281, NM_001204280, NM_001204279, NM_001204278, NM_001204277, NM_001204276, NM_001204275, BC057332,
Species
mouse
UniGene ID
Mm.384027

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.