mouse GPC1 shRNA silencing Adenovirus

Name
Ad-m-GPC1-shRNA

Cat No
shADV-260500

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Gpc1.

shADV-260500

Ad-m-GPC1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Gpc1 (glypican 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

AI462976

Description (Vector)

Cell surface proteoglycan that bears heparan sulfate. Binds, via the heparan sulfate side chains, alpha-4 (V) collagen and participates in Schwann cell myelination (By similarity). May act as a catalyst in increasing the rate of conversion of prion protein PRPN(C) to PRNP(Sc) via associating (via the heparan sulfate side chains) with both forms of PRPN, targeting them to lipid rafts and facilitating their interaction. Required for proper skeletal muscle differentiation by sequestering FGF2 in lipid rafts preventing its binding to receptors (FGFRs) and inhibiting the FGF-mediated signaling.

Gene ID

14733

Gene Name (Vector)

glypican 1

Gene Symbol

Gpc1

ORF Size (aa)

1674

ORF Size (bp)

1674 bp

RefSeq ID

NM_016696

RefSeq Synonyms

NM_016696, BC062902,

Species

mouse

UniGene ID

Mm.297976

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.