mouse GOPC shRNA silencing Adenovirus

Name 
Ad-m-GOPC-shRNA
Cat No 
shADV-260459
Availability
Immediate

This is an Adenovirus expressing shRNA for silencing of Mouse Gopc.

shADV-260459
Ad-m-GOPC-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Gopc (golgi associated PDZ and coiled-coil motif containing). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
2210402P09Rik; AI844555; CAL; FIG; GOPC1; PIST
Description (Vector)
Plays a role in intracellular protein trafficking and degradation. May regulate CFTR chloride currents and acid-induced ASIC3 currents by modulating cell surface expression of both channels. May also regulate the intracellular trafficking of the ADR1B receptor. May play a role in autophagy. Overexpression results in CFTR intracellular retention and degradation in the lysosomes.
Gene ID
94221
Gene Name (Vector)
golgi associated PDZ and coiled-coil motif containing
Gene Symbol
Gopc
ORF Size (aa)
1368
ORF Size (bp)
1368 bp
RefSeq ID
NM_053187
RefSeq Synonyms
NM_053187, NM_001199272, BC051171,
Species
mouse
UniGene ID
Mm.390258

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.