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mouse GCET2 shRNA silencing Adenovirus

Name 
Ad-m-GCET2-shRNA
Cat No 
shADV-259974
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Gcsam.

shADV-259974
Ad-m-GCET2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Gcsam (germinal center associated, signaling and motility). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Gcet; Gcet2; M17; M17-L
Description (Vector)
Involved in the negative regulation of lymphocyte motility. It mediates the migration-inhibitory effects of IL6. Serves as a positive regulator of the RhoA signaling pathway. Enhancement of RhoA activation results in inhibition of lymphocyte and lymphoma cell motility by activation of its downstream effector ROCK.
Gene ID
14525
Gene Name (Vector)
germinal center associated, signaling and motility
Gene Symbol
Gcsam
ORF Size (aa)
480
RefSeq ID
NM_008099
RefSeq Synonyms
NM_008099, NM_001159297, BC099585,
Species
mouse
UniGene ID
Mm.4799

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.