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mouse FYB shRNA silencing Adenovirus

Name 
Ad-m-FYB-shRNA
Cat No 
shADV-259738
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Fyb.

shADV-259738
Ad-m-FYB-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Fyb (FYN binding protein). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
ADAP; B630013F22Rik; FYB-120/130; p120/130; p120/p130; Slap130
Description (Vector)
Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells. Modulates the expression of interleukin-2 (IL-2). Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2. May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton.
Gene ID
23880
Gene Name (Vector)
FYN binding protein
Gene Symbol
Fyb
ORF Size (aa)
2460
ORF Size (bp)
2460 bp
RefSeq ID
NM_011815
RefSeq Synonyms
NM_011815, NM_001278269, BC141352,
Species
mouse
UniGene ID
Mm.170905

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.