mouse FTO shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Fto.
shADV-259684
Ad-m-FTO-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Fto (fat mass and obesity associated). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AW743446; mKIAA1752
Description (Vector)
Dioxygenase that repairs alkylated DNA and RNA by oxidative demethylation. Has highest activity towards single-stranded RNA containing 3-methyluracil, followed by single-stranded DNA containing 3-methylthymine. Has low demethylase activity towards single-stranded DNA containing 1-methyladenine or 3-methylcytosine. Has no activity towards 1-methylguanine. Has no detectable activity towards double-stranded DNA. Requires molecular oxygen, alpha-ketoglutarate and iron. Contributes to the regulation of the global metabolic rate, energy expenditure and energy homeostasis. Contributes to the regulation of body size and body fat accumulation.
Gene ID
26383
Gene Name (Vector)
fat mass and obesity associated
Gene Symbol
Fto
ORF Size (aa)
1509
ORF Size (bp)
1509 bp
RefSeq ID
NM_011936
RefSeq Synonyms
NM_011936, BC057008, BC022222,
Species
mouse
UniGene ID
Mm.4375
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.