mouse FOXA3 shRNA silencing Adenovirus
Category: Adenovirus > shRNA-Silencing
Cat. No: shADV-259552
Availability:
Immediate
Name:
Ad-m-FOXA3-shRNA
This is an Adenovirus expressing shRNA for silencing of Mouse Foxa3.
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Product Info
- Knockdown
- >90% knockdown of mRNA in cultured cells
Viral Details
- Viral Backbone
- Human Adenovirus Type5 (dE1/E3)
- Promoter
- U6
- Reporter
- eGFP (default), optional CFP, YFP, RFP, mCherry
- Storage Buffer
- DMEM, 2% BSA, 2.5% Glycerol
Gene Details
- Species
- Mouse
- Gene Symbol
- Foxa3
- Gene Name
- forkhead box A3
- Gene ID
- 15377
- Gene Synonyms
- Hnf-3g; Hnf3g; Tcf-3g; Tcf3g
- ORF Size
- 1062 bp
- RefSeq#
- NM_008260
- Gene Description
- Transcription factor that is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites (By similarity). Originally described as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; binds to and activates transcription from the G6PC promoter. Binds to the CYP3A4 promoter and activates its transcription in cooperation with CEBPA. Binds to the CYP3A7 promoter together with members of the CTF/NF-I family. Involved in regulation of neuronal-specific transcription. May be involved in regulation of spermatogenesis.
- UniGene ID
- Mm.472695
Product Citations
This product is referenced in the following publications:
Related Products
Product | Cat No. |
---|---|
AAV-h-FOXA3 | AAV-209227 |
AAV-m-FOXA3 | AAV-259552 |
Ad-h-FOXA3 | ADV-209227 |
Ad-m-FOXA3 | ADV-259552 |
AAV-h-FOXA3-shRNA | shAAV-209227 |
AAV-m-FOXA3-shRNA | shAAV-259552 |
Ad-h-FOXA3-shRNA | shADV-209227 |
Control Products
Product | Cat No. |
---|---|
Ad-GFP-U6-shRNA | 1122 |
Ad-U6-Luc-RNAi | 1123 |
Ad-U6-RNAi | 1640 |
Ad-U6-shRNA-CFP | 1780 |
Ad-U6-shRNA-mCherry | 1781 |
Ad-U6-shRNA-RFP | 1782 |
Ad-U6-shRNA-YFP | 1783 |
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