mouse FBXO3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Fbxo3.
shADV-259233
Ad-m-FBXO3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Fbxo3 (F-box protein 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1200002G09Rik; 1700026K02Rik; AI046358; Fba
Description (Vector)
Substrate recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. In the presence of PML, HIPK2 ubiquitination still occurs, but degradation is prevented. PML, HIPK2 and FBXO3 may act synergically to activate p53/TP53-dependent transactivation.
Gene ID
57443
Gene Name (Vector)
F-box protein 3
Gene Symbol
Fbxo3
ORF Size (aa)
1443
ORF Size (bp)
1443 bp
RefSeq ID
NM_020593
RefSeq Synonyms
NM_212433, NM_020593, BC058253,
Species
mouse
UniGene ID
Mm.143768
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.