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mouse FANCM shRNA silencing Adenovirus

Name 
Ad-m-FANCM-shRNA
Cat No 
shADV-259152
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Fancm.

shADV-259152
Ad-m-FANCM-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Fancm (Fanconi anemia, complementation group M). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AI427100; C730036B14Rik; D12Ertd364e
Description (Vector)
ATPase required for FANCD2 ubiquitination, a key reaction in DNA repair. Binds to ssDNA but not to dsDNA. Recruited to forks stalled by DNA interstrand cross-links, and required for cellular resistance to such lesions.
Gene ID
104806
Gene Name (Vector)
Fanconi anemia, complementation group M
Gene Symbol
Fancm
ORF Size (aa)
6066
ORF Size (bp)
6066 bp
RefSeq ID
NM_178912
RefSeq Synonyms
NM_178912, BC150785,
Species
mouse
UniGene ID
Mm.374847

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.