mouse EMD shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Emd.
shADV-258322
Ad-m-EMD-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Emd (emerin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AW550900; Sta
Description (Vector)
Stabilizes and promotes the formation of a nuclear actin cortical network. Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments. Inhibits beta-catenin activity by preventing its accumulation in the nucleus. Acts by influencing the nuclear accumulation of beta-catenin through a CRM1-dependent export pathway. Links centrosomes to the nuclear envelope via a microtubule association. EMD and BAF are cooperative cofactors of HIV-1 infection. Association of EMD with the viral DNA requires the presence of BAF and viral integrase. The association of viral DNA with chromatin requires the presence of BAF and EMD. Required for proper localization of non-farnesylated prelamin-A/C.
Gene ID
13726
Gene Name (Vector)
emerin
Gene Symbol
Emd
ORF Size (aa)
780
RefSeq ID
NM_007927
RefSeq Synonyms
NM_007927, BC132133, BC132131,
Species
mouse
UniGene ID
Mm.18892
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.