mouse EIF6 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Eif6.
shADV-258262
Ad-m-EIF6-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Eif6 (eukaryotic translation initiation factor 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1110004P11; AA408895; CAB; eIF-6; imc-415; Itgb4bp; p27(BBP); p27BBP
Description (Vector)
Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May behave as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (GNB2L1)-dependent protein kinase C activity.
Gene ID
16418
Gene Name (Vector)
eukaryotic translation initiation factor 6
Gene Symbol
Eif6
ORF Size (aa)
738
ORF Size (bp)
738 bp
RefSeq ID
NM_010579
RefSeq Synonyms
NM_010579, BC024442, BC015274,
Species
mouse
UniGene ID
Mm.271674
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.