mouse EFNB3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Efnb3.
shADV-257821
Ad-m-EFNB3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Efnb3 (ephrin B3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
EFL-6; ELF-3; Elk-L3; Epl8; LERK-8; NLERK-2
Description (Vector)
Cell surface transmembrane ligand for Eph receptors, a family of receptor tyrosine kinases which are crucial for migration, repulsion and adhesion during neuronal, vascular and epithelial development. Binds promiscuously Eph receptors residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. May play a pivotal role in forebrain function. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons (By similarity).
Gene ID
13643
Gene Name (Vector)
ephrin B3
Gene Symbol
Efnb3
ORF Size (aa)
1023
ORF Size (bp)
1023 bp
RefSeq ID
NM_007911
RefSeq Synonyms
NM_007911, BC058617, BC052001,
Species
mouse
UniGene ID
Mm.249637
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.