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mouse DVL2 shRNA silencing Adenovirus

Name 
Ad-m-DVL2-shRNA
Cat No 
shADV-257560
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Dvl2.

shADV-257560
Ad-m-DVL2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Dvl2 (dishevelled segment polarity protein 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)
Participates in Wnt signaling by binding to the cytoplasmic C-terminus of frizzled family members and transducing the Wnt signal to down-stream effectors. Promotes internalization and degradation of frizzled proteins upon Wnt signaling. Plays a role both in canonical and non-canonical Wnt signaling. Plays a role in the signal transduction pathways mediated by multiple Wnt genes (By similarity).
Gene ID
13543
Gene Name (Vector)
dishevelled segment polarity protein 2
Gene Symbol
Dvl2
ORF Size (aa)
2211
ORF Size (bp)
2211 bp
RefSeq ID
NM_007888
RefSeq Synonyms
NM_007888, BC092396, BC053050,
Species
mouse
UniGene ID
Mm.5114

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.