mouse DIO3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Dio3.
shADV-257184
Ad-m-DIO3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Dio3 (deiodinase, iodothyronine type III). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Description (Vector)
Responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into RT3 (3,3',5'-triiodothyronine) and of T3 (3,5,3'-triiodothyronine) into T2 (3,3'-diiodothyronine). RT3 and T2 are inactive metabolites. May play a role in preventing premature exposure of developing fetal tissues to adult levels of thyroid hormones. Can regulate circulating fetal thyroid hormone concentrations throughout gestation. Essential role for regulation of thyroid hormone inactivation during embryological development.
Gene ID
107585
Gene Name (Vector)
deiodinase, iodothyronine type III
Gene Symbol
Dio3
ORF Size (aa)
837
RefSeq ID
NM_172119
RefSeq Synonyms
NM_172119, BC106848, BC106847,
Species
mouse
UniGene ID
Mm.154427
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.