mouse DEF6 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Def6.
shADV-256979
Ad-m-DEF6-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Def6 (differentially expressed in FDCP 6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2410003F05Rik; 6430538D02Rik; AV094905; Ibp; Slat; Slat2; Slat6
Description (Vector)
Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which plays a role in the activation of Rho GTPases RAC1, RhoA and CDC42. Can regulate cell morphology in cooperation with activated RAC1. Plays a role in Th2 (T helper cells) development and/or activation, perhaps by interfering with ZAP70 signaling (By similarity).
Gene ID
23853
Gene Name (Vector)
differentially expressed in FDCP 6
Gene Symbol
Def6
ORF Size (aa)
1893
ORF Size (bp)
1893 bp
RefSeq ID
NM_027185
RefSeq Synonyms
NM_027185, BC131953, BC120500,
Species
mouse
UniGene ID
Mm.204731
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.