mouse DDX11 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Ddx11.
shADV-256919
Ad-m-DDX11-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Ddx11 (DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
4732462I11Rik; CHL1; CHLR1; essa15a; KRG2
Description (Vector)
DNA helicase involved in cellular proliferation. Possesses DNA-dependent ATPase and helicase activities. This helicase translocates on single-stranded DNA in the 5' to 3' direction in the presence of ATP and, to a lesser extent, dATP. Its unwinding activity requires a 5'-single-stranded region for helicase loading, since flush-ended duplex structures do not support unwinding. The helicase activity is capable of displacing duplex regions up to 100 bp, which can be extended to 500 bp by RPA or the cohesion establishment factor, the Ctf18-RFC (replication factor C) complex activities. Stimulates the flap endonuclease activity of FEN1. Required for normal sister chromatid cohesion. Required for recruitment of bovine papillomavirus type 1 regulatory protein E2 to mitotic chrmosomes and for viral genome maintenance. Required for maintaining the chromosome segregation and is essential for embryonic development and the prevention of aneuploidy. May function during either S, G2, or M phase of the cell cycle. Binds to both single- and double-stranded DNA.
Gene ID
320209
Gene Name (Vector)
DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
Gene Symbol
Ddx11
ORF Size (aa)
2643
ORF Size (bp)
2643 bp
RefSeq ID
NM_001003919
RefSeq Synonyms
NM_001003919, BC079656,
Species
mouse
UniGene ID
Mm.259605
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.