mouse CRY2 shRNA silencing Adenovirus

Name 
Ad-m-CRY2-shRNA
Cat No 
shADV-256161
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse CRY2.

shADV-256161
Ad-m-CRY2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse CRY2 (cryptochrome 2 (photolyase-like)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AV006279; D130054K12Rik
Description (Vector)
Blue light-dependent regulator of the circadian feedback loop. Inhibits CLOCK NPAS2-ARNTL E box-mediated transcription. Acts, in conjunction with CRY2, in maintaining period length and circadian rhythmicity. Has no photolyase activity. Capable of translocating circadian clock core proteins such as PER proteins to the nucleus. May inhibit CLOCK NPAS2-ARNTL transcriptional activity through stabilizing the unphosphorylated form of ARNTL.
Gene ID
12953
Gene Name (Vector)
cryptochrome 2 (photolyase-like)
Gene Symbol
CRY2
ORF Size (aa)
1779
ORF Size (bp)
1779 bp
RefSeq ID
NM_009963
RefSeq Synonyms
NM_009963, NM_001113333, BC066799, BC054794,
Species
mouse
UniGene ID
Mm.254181

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.