mouse COPE shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Cope.
shADV-255909
Ad-m-COPE-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Cope (coatomer protein complex, subunit epsilon). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1110005D17Rik; Cope1
Description (Vector)
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity).
Gene ID
59042
Gene Name (Vector)
coatomer protein complex, subunit epsilon
Gene Symbol
Cope
ORF Size (aa)
927
RefSeq ID
NM_021538
RefSeq Synonyms
NM_021538, BC083336, BC009170,
Species
mouse
UniGene ID
Mm.28668
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.