mouse CENPN shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Cenpn.
shADV-255269
Ad-m-CENPN-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Cenpn (centromere protein N). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2610510J17Rik; AI426416; AW545024
Description (Vector)
Component of the CENPA-NAC (nucleosome-associated) complex, a complex that plays a central role in assembly of kinetochore proteins, mitotic progression and chromosome segregation. The CENPA-NAC complex recruits the CENPA-CAD (nucleosome distal) complex and may be involved in incorporation of newly synthesized CENPA into centromeres. CENPN is the first protein to bind specifically to CENPA nucleosomes and the direct binding of CENPA nucleosomes by CENPN is required for centromere assembly. Required for chromosome congression and efficiently align the chromosomes on a metaphase plate.
Gene ID
72155
Gene Name (Vector)
centromere protein N
Gene Symbol
Cenpn
ORF Size (aa)
753
ORF Size (bp)
753 bp
RefSeq ID
NM_028131
RefSeq Synonyms
NM_028131, BC058243,
Species
mouse
UniGene ID
Mm.23185
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.