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mouse CACNA1H shRNA silencing Adenovirus

Name 
Ad-m-CACNA1H-shRNA
Cat No 
shADV-254367
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Cacna1h.

shADV-254367
Ad-m-CACNA1H-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Cacna1h (calcium channel, voltage-dependent, T type, alpha 1H subunit). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
alpha13.2; Cav3.2; MNCb-1209
Description (Vector)
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1H gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by nickel and mibefradil. A particularity of this type of channels is an opening at quite negative potentials, and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes.
Gene ID
58226
Gene Name (Vector)
calcium channel, voltage-dependent, T type, alpha 1H subunit
Gene Symbol
Cacna1h
ORF Size (aa)
7080
ORF Size (bp)
7080 bp
RefSeq ID
NM_021415
RefSeq Synonyms
NM_021415, NM_001163691, BC138026,
Species
mouse
UniGene ID
Mm.268378

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.