mouse ATG4A shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Atg4a.
shADV-253221
Ad-m-ATG4A-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Atg4a (autophagy related 4A, cysteine peptidase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AI627006; Apg4a; Atg4al; Autl2; AV169859
Description (Vector)
Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A subpopulation of form I is subsequently converted to a smaller form (form II). Form II, with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine (PE)-conjugated form, and has the capacity for the binding to autophagosomes. Preferred substrate is GABARAPL2 followed by MAP1LC3A and GABARAP.
Gene ID
666468
Gene Name (Vector)
autophagy related 4A, cysteine peptidase
Gene Symbol
Atg4a
ORF Size (aa)
1191
ORF Size (bp)
1191 bp
RefSeq ID
NM_174875
RefSeq Synonyms
NM_174875, BC089500,
Species
mouse
UniGene ID
Mm.393320
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.