mouse ASXL1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Asxl1.
shADV-253182
Ad-m-ASXL1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Asxl1 (additional sex combs like 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
mKIAA0978
Description (Vector)
Probable Polycomb group (PcG) protein involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as retinoic acid receptors (RARs) and peroxisome proliferator-activated receptor gamma (PPARG). Acts as coactivator of RARA and RXRA through association with NCOA1. Acts as corepressor through recruitment of KDM1A and CBX5 to target genes in a cell-type specific manner; the function seems to involve differential recruitment of methylated histone H3 to respective promoters. Acts as corepressor for PPARG and suppresses its adipocyte differentiation-inducing activity (By similarity). Non-catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-119' (H2AK119ub1).
Gene ID
228790
Gene Name (Vector)
additional sex combs like 1
Gene Symbol
Asxl1
ORF Size (aa)
4545
ORF Size (bp)
4545 bp
RefSeq ID
NM_001039939
RefSeq Synonyms
NM_001039939, BC172725, BC172612,
Species
mouse
UniGene ID
Mm.330677
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.