mouse APTX shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Aptx.
shADV-252871
Ad-m-APTX-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Aptx (aprataxin). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2410016G21Rik; AA388047; FHA-HIT
Description (Vector)
DNA-binding protein involved in single-strand DNA break repair, double-strand DNA break repair and base excision repair. Resolves abortive DNA ligation intermediates formed either at base excision sites, or when DNA ligases attempt to repair non-ligatable breaks induced by reactive oxygen species. Catalyzes the release of adenylate groups covalently linked to 5'-phosphate termini, resulting in the production of 5'-phosphate termini that can be efficiently rejoined. Also able to hydrolyze adenosine 5'-monophosphoramidate (AMP-NH(2)) and diadenosine tetraphosphate (AppppA), but with lower catalytic activity.
Gene ID
66408
Gene Name (Vector)
aprataxin
Gene Symbol
Aptx
ORF Size (aa)
1008
ORF Size (bp)
1008 bp
RefSeq ID
NM_025545
RefSeq Synonyms
NM_025545, NM_001025445, NM_001025444, BC021872,
Species
mouse
UniGene ID
Mm.430710
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.