mouse APLP1 shRNA silencing Adenovirus

Name 
Ad-m-APLP1-shRNA
Cat No 
shADV-252824
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Aplp1.

shADV-252824
Ad-m-APLP1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Aplp1 (amyloid beta (A4) precursor-like protein 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
92
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Description (Vector)
APLP1 may play a role in postsynaptic function. The C-terminal gamma-secretase processed fragment, ALID1, activates transcription activation through APBB1 (Fe65) binding (By similarity). Couples to JIP signal transduction through C-terminal binding. May interact with cellular G-protein signaling pathways. Can regulate neurite outgrowth through binding to components of the extracellular matrix such as heparin and collagen I|Function: The gamma-CTF peptide, C30, is a potent enhancer of neuronal apoptosis (By similarity).
Gene ID
11803
Gene Name (Vector)
amyloid beta (A4) precursor-like protein 1
Gene Symbol
Aplp1
ORF Size (aa)
1965
ORF Size (bp)
1965 bp
RefSeq ID
NM_007467
RefSeq Synonyms
NM_007467, BC021877,
Species
mouse
UniGene ID
Mm.2381

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.