mouse APH1B shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Aph1b.
shADV-252814
Ad-m-APH1B-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Aph1b (aph1 homolog B, gamma secretase subunit). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
2310057K14Rik; Aph1c
Description (Vector)
Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral proteins such as Notch receptors and APP (beta-amyloid precursor protein). It probably represents a stabilizing cofactor for the presenilin homodimer that promotes the formation of a stable complex. Probably present in a minority of gamma-secretase complexes compared to APH1A.
Gene ID
208117
Gene Name (Vector)
aph1 homolog B, gamma secretase subunit
Gene Symbol
Aph1b
ORF Size (aa)
774
RefSeq ID
NM_177583
RefSeq Synonyms
NM_177583, BC079659,
Species
mouse
UniGene ID
Mm.41291
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.