mouse ANPEP shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Anpep.
shADV-252731
Ad-m-ANPEP-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Anpep (alanyl (membrane) aminopeptidase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
AP-M; AP-N; Apn; Cd13; P150
Description (Vector)
Broad specificity aminopeptidase. Plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. May play a critical role in the pathogenesis of cholesterol gallstone disease. May be involved in the metabolism of regulatory peptides of diverse cell types including small intestinal and tubular epithelial cells, macrophages, granulocytes and synaptic membranes from the CNS. Found to cleave antigen peptides bound to major histocompatibility complex class II molecules of presenting cells and to degrade neurotransmitters at synaptic junctions. Is also implicated as a regulator of IL-8 bioavailability in the endometrium, and therefore may contribute to the regulation of angiogenesis. Is used as a marker for acute myeloid leukemia and plays a role in tumor invasion. In case of human coronavirus 229E (HCoV-229E) infection, serves as receptor for HCoV-229E spike glycoprotein. Mediates as well human cytomegalovirus (HCMV) infection.
Gene ID
16790
Gene Name (Vector)
alanyl (membrane) aminopeptidase
Gene Symbol
Anpep
ORF Size (aa)
2901
ORF Size (bp)
2901 bp
RefSeq ID
NM_008486
RefSeq Synonyms
NM_008486, BC040792, BC017011, BC005431,
Species
mouse
UniGene ID
Mm.4487
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.