mouse ALKBH3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Mouse Alkbh3.
shADV-252515
Ad-m-ALKBH3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Alkbh3 (alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
1700108H04Rik; 1810020C19Rik; Abh3; mABH3
Description (Vector)
Dioxygenase that repairs alkylated DNA containing 1-methyladenine (1meA) and 3-methylcytosine (3meC) by oxidative demethylation. Has a strong preference for single-stranded DNA. Able to process alkylated 3mC within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKHB3. May also act on RNA. Requires molecular oxygen, alpha-ketoglutarate and iron.
Gene ID
69113
Gene Name (Vector)
alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase
Gene Symbol
Alkbh3
ORF Size (aa)
861
ORF Size (bp)
861 bp
RefSeq ID
NM_026944
RefSeq Synonyms
NM_026944, BC018196,
Species
mouse
UniGene ID
Mm.272498
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.