mouse AGRN shRNA silencing Adenovirus

Name 
Ad-m-AGRN-shRNA
Cat No 
shADV-252246
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Mouse Agrn.

shADV-252246
Ad-m-AGRN-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Agrn (agrin). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
Agrin; nmf380
Description (Vector)
Plays a central role in the formation and the maintenance of the neuromuscular junction (NMJ), the synapse between motor neuron and skeletal muscle. Ligand of the MUSK signaling complex that directly binds LRP4 in this complex and induces the phosphorylation of MUSK, the kinase of the complex. The activation of MUSK in myotubes induces the formation of NMJ by regulating different processes including the transcription of specific genes and the clustering of AChR in the postsynaptic membrane (By similarity).
Gene ID
11603
Gene Name (Vector)
agrin
Gene Symbol
Agrn
ORF Size (aa)
5601
ORF Size (bp)
5601 bp
RefSeq ID
NM_021604
RefSeq Synonyms
NM_021604, BC150703,
Species
mouse
UniGene ID
Mm.273098

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.