mouse ADH7 shRNA silencing Adenovirus

Product Info

Knockdown

>90% knockdown of mRNA in cultured cells

Viral Details

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Promoter

U6

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Gene Details

Species

Mouse

Gene Symbol

Adh7

Gene Name

alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide

Gene ID

11529

Gene Synonyms

Adh-3; Adh-3e; Adh-3t; Adh3; Adh3-e; Adh3-t; Adh4; Adt-1; AI325182

ORF Size

1125 bp

RefSeq#

NM_009626

Gene Description

Could function in retinol oxidation for the synthesis of retinoic acid, a hormone important for cellular differentiation. Medium-chain (octanol) and aromatic (m-nitrobenzaldehyde) compounds are the best substrates. Ethanol is not a good substrate but at the high ethanol concentrations reached in the digestive tract, it plays a role in the ethanol oxidation and contributes to the first pass ethanol metabolism.

UniGene ID

Mm.8473