mouse ADAMTS5 shRNA silencing Adenovirus

Name 
Ad-m-ADAMTS5-shRNA
Cat No 
shADV-252096
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Adamts5.

shADV-252096
Ad-m-ADAMTS5-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Adamts5 (a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
9530092O11Rik; ADAM-TS5; ADAMTS1; ADAMTS11; ADMP-2; AI481094; ASMP-2
Description (Vector)
Cleaves aggrecan, a cartilage proteoglycan, and may be involved in its turnover. May play an important role in the destruction of aggrecan in arthritic diseases. May play a role in proteolytic processing mostly during the peri-implantation period.
Gene ID
23794
Gene Name (Vector)
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)
Gene Symbol
Adamts5
ORF Size (aa)
2793
ORF Size (bp)
2793 bp
RefSeq ID
NM_011782
RefSeq Synonyms
NM_011782, BC138620, BC138619,
Species
mouse
UniGene ID
Mm.437478

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.