mouse UBE3C shRNA silencing Adenovirus

Name 
Ad-m-UBE3C-shRNA
Cat No 
shADV-251714
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Ube3c.

shADV-251714
Ad-m-UBE3C-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Ube3c (ubiquitin protein ligase E3C). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AI853514; mKIAA0010
Description (Vector)
E3 ubiquitin-protein ligase that accepts ubiquitin from the E2 ubiquitin-conjugating enzyme UBE2D1 in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Can assemble unanchored poly-ubiquitin chains in either 'Lys-29'- or 'Lys-48'-linked polyubiquitin chains. Has preference for 'Lys-48' linkages. It can target itself for ubiquitination in vitro and may promote its own degradation in vivo.
Gene ID
100763
Gene Name (Vector)
ubiquitin protein ligase E3C
Gene Symbol
Ube3c
ORF Size (aa)
3252
ORF Size (bp)
3252 bp
RefSeq ID
NM_133907
RefSeq Synonyms
NM_133907, BC137626, BC120731,
Species
mouse
UniGene ID
Mm.137746

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.