mouse 1110032A04RIK shRNA silencing Adenovirus

Name 
Ad-m-1110032A04RIK-shRNA
Cat No 
shADV-250141
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Mouse Sptssb.

shADV-250141
Ad-m-1110032A04RIK-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Mouse Sptssb (serine palmitoyltransferase, small subunit B). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
1110032A04Rik; ADMP; Sssptb
Description (Vector)
Stimulates the activity of serine palmitoyltransferase (SPT). The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference, complexes with this subunit showing a clear preference for longer acyl-CoAs. The SPTLC1-SPTLC2-SPTSSB complex shows a strong preference for C18-CoA substrate, while the SPTLC1-SPTLC3-SPTSSB isozyme displays an ability to use a broader range of acyl-CoAs, without apparent preference. May play a role in signal transduction.
Gene ID
66183
Gene Name (Vector)
serine palmitoyltransferase, small subunit B
Gene Symbol
Sptssb
ORF Size (aa)
231
RefSeq ID
NM_133675
RefSeq Synonyms
NM_133675, NM_001286959, NM_001164210, BC022628,
Species
mouse
UniGene ID
Mm.45481

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.