human CD97 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ADGRE5.
shADV-232657
Ad-h-CD97-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ADGRE5 (adhesion G protein-coupled receptor E5). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CD97; TM7LN1
Description (Vector)
CD97 encodes a member of the EGF-TM7 subfamily of adhesion G protein-coupled receptors, which mediate cell-cell interactions. These proteins are cleaved by self-catalytic proteolysis into a large extracellular subunit and seven-span transmembrane subunit, which associate at the cell surface as a receptor complex. The encoded protein may play a role in cell adhesion as well as leukocyte recruitment, activation and migration, and contains multiple extracellular EGF-like repeats which mediate binding to chondroitin sulfate and the cell surface complement regulatory protein CD55. Expression of this gene may play a role in the progression of several types of cancer. Alternatively spliced transcript variants encoding multiple isoforms with 3 to 5 EGF-like repeats have been observed for this gene. CD97 is found in a cluster with other EGF-TM7 genes on the short arm of chromosome 19.
Gene ID
976
Gene Name (Vector)
adhesion G protein-coupled receptor E5
Gene Symbol
ADGRE5
HGNC ID
HGNC:1711
ORF Size (aa)
2229
ORF Size (bp)
2229 bp
RefSeq ID
NM_078481
RefSeq Synonyms
NM_078481, NM_001784, NM_001025160, BC026690,
Species
human
UniGene ID
Hs.
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.