human CLDN10 shRNA silencing Adenovirus

Name 
Ad-h-CLDN10-shRNA
Cat No 
shADV-231872
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human CLDN10.

shADV-231872
Ad-h-CLDN10-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CLDN10 (claudin 10). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CPETRL3; OSP-L
Description (Vector)
CLDN10 encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. The expression level of this gene is associated with recurrence of primary hepatocellular carcinoma. Six alternatively spliced transcript variants encoding different isoforms have been reported, but the transcript sequences of some variants are not determined.
Gene ID
9071
Gene Name (Vector)
claudin 10
Gene Symbol
CLDN10
ORF Size (aa)
687
ORF Size (bp)
687 bp
RefSeq ID
NM_006984
RefSeq Synonyms
NM_182848, NM_006984, NM_001160100, BC010920,
Species
human
UniGene ID
Hs.534377

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.