human CLDN4 shRNA silencing Adenovirus

Name
Ad-h-CLDN4-shRNA

Cat No
shADV-231624

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human CLDN4.

shADV-231624

Ad-h-CLDN4-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CLDN4 (claudin 4). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

CPE-R; CPER; CPETR; CPETR1; hCPE-R; WBSCR8

Description (Vector)

CLDN4 encodes an integral membrane protein, which belongs to the claudin family. The protein is a component of tight junction strands and may play a role in internal organ development and function during pre- and postnatal life. CLDN4 is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.

Gene ID

1364

Gene Name (Vector)

claudin 4

Gene Symbol

CLDN4

HGNC ID

HGNC:2046

ORF Size (aa)

630

ORF Size (bp)

630 bp

RefSeq ID

NM_001305

RefSeq Synonyms

NM_001305, BC000671,

Species

human

UniGene ID

Hs.699253

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.