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human AGTR1 shRNA silencing Adenovirus

Name 
Ad-h-AGTR1-shRNA
Cat No 
shADV-231320
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human AGTR1.

shADV-231320
Ad-h-AGTR1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human AGTR1 (angiotensin II receptor type 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AG2S; AGTR1B; AT1; AT1AR; AT1B; AT1BR; AT1R; AT2R1; HAT1R
Description (Vector)
Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion. It is an important effector controlling blood pressure and volume in the cardiovascular system. It acts through at least two types of receptors. This gene encodes the type 1 receptor which is thought to mediate the major cardiovascular effects of angiotensin II. This gene may play a role in the generation of reperfusion arrhythmias following restoration of blood flow to ischemic or infarcted myocardium. It was previously thought that a related gene, denoted as AGTR1B, existed; however, it is now believed that there is only one type 1 receptor gene in humans. Multiple alternatively spliced transcript variants have been reported for this gene.
Gene ID
185
Gene Name (Vector)
angiotensin II receptor type 1
Gene Symbol
AGTR1
HGNC ID
HGNC:336
ORF Size (aa)
1080
ORF Size (bp)
1080 bp
RefSeq ID
NM_032049
RefSeq Synonyms
NM_032049, NM_031850, NM_009585, NM_004835, NM_000685, BC068494, BC022447,
Species
human
UniGene ID
Hs.719071

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.