human CNR2 shRNA silencing Adenovirus

Name 
Ad-h-CNR2-shRNA
Cat No 
shADV-230865
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human CNR2.

shADV-230865
Ad-h-CNR2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human CNR2 (cannabinoid receptor 2 (macrophage)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CB-2; CB2; CX5
Description (Vector)
The cannabinoid delta-9-tetrahydrocannabinol is the principal psychoactive ingredient of marijuana. The proteins encoded by this gene and the cannabinoid receptor 1 (brain) (CNR1) gene have the characteristics of a guanine nucleotide-binding protein (G-protein)-coupled receptor for cannabinoids. They inhibit adenylate cyclase activity in a dose-dependent, stereoselective, and pertussis toxin-sensitive manner. These proteins have been found to be involved in the cannabinoid-induced CNS effects (including alterations in mood and cognition) experienced by users of marijuana. The cannabinoid receptors are members of family 1 of the G-protein-coupled receptors.
Gene ID
1269
Gene Name (Vector)
cannabinoid receptor 2 (macrophage)
Gene Symbol
CNR2
HGNC ID
HGNC:2160
ORF Size (aa)
1083
RefSeq ID
NM_001841
RefSeq Synonyms
NM_001841, BC074767, BC069722,
Species
human
UniGene ID
Hs.73037

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.